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Read our Do-Si-Dos strain review to find out about this indica hybrid's calming effects and pungent aroma. Named after the popular peanut butter Girl Scout Cookies, Do-Si-Dos offers potent and long-lasting effects.

Its high potency delivers an initial cerebral jolt followed by a blissful haze of relaxation. If you're a Cookies strain lover, you'll definitely want to get your hands on this hybrid.

Strain Profile: Do-Si-Dos

Marijuana in bag, do-si-dos strain

Is Do-Si-Do strain an Indica or Sativa?

Popular among growers and users, Do-Si-Dos is an indica-dominant hybrid strain with higher-than-average THC levels. Its flowers typically contain between 18% to 22% THC.  CBD levels are usually under 1%. That means you'll get an unadulterated dose of intoxicating THC time after time. It also features an extraordinary flavor and smell making each smoking or vaping session a pleasure.

Do-Si-Dos is perfect for indica strain lovers who want to feel happy, relaxed, and pain-free. Its knock-out effects and body high can be too much for first-time and low-tolerance users.

Beginners: tread lightly with this indica. In small-to-moderate doses, this strain offers a supremely relaxing experience. Stressful thoughts disappear and muscle aches and pains are dulled. It's a versatile indica strain, perfect for recreational and medical users.

Average THC Level: 20%

Average CBD Level: <1%

Strain Type: Indica

Genetics: OG Kush Breath (OGKB) x Face Off OG

Breeder: Archive Seed Bank

Terpenes: Limonene, Caryophyllene, Linalool

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Do-Si-Dos Strain History & Genetics

Created in 2016 by Oregon-based Archive Seed Bank, Do-Si-Dos built its claim to fame in Portland. As its popularity grew, the strain made its way down the West Coast and eventually reached the Colorado market. The rest is history. 

Archive breeder, ThaDocta, captured the signature Cookies essence by crossing OG Kush Breath (OGKB), a phenotype of Girl Scout Cookies (GSC), with Face Off OG. Face Off OG's narcotic-like effects bring the face-melting potency, while the OGKB balances it out with its clear-headed and relaxing effects.


Do-Si-Dos strain has a unique flavor that will excite your taste buds on the inhale and exhale. A burst of bright lemon and lime flavors instantly coats your palate.  The tart, citrus flavor is balanced by a subtle floral sweetness. 

Hints of earthy pine, soil, and diesel add to the complexity of the taste. OG and Kush flavors unite to bring you a balanced mix of doughy sweetness and spicy earthiness. It tastes good enough to eat.


If you love OG aromas, you'll love this strain's invigorating mix of citrus, pepper, and floral notes. Pungent, sweet, and funky at the same time. This indica-dominant hybrid strain has a rich and earthy smell paired with strong notes of lavender and citrus.

Slightly nutty and doughy notes are overshadowed by its sweet and funky scents. Its limonene (citrus), caryophyllene (pepper), and linalool (floral) terpenes add to the euphoric and relaxing effects.


Do-Si-Dos' high THC content delivers blissful, calming, and sedative effects. If you're looking for a stoney experience, this indica-dominant hybrid strain is for you. Initially, you'll feel a rush of euphoria flood your brain leaving you happy and stress-free.

However, these energizing effects taper off into a relaxing and comfortable experience. A serene mindstate is followed by slightly narcotic effects that can deliver a body buzz from head to toe.

For medical users, this indica hybrid strain offers potent medicinal effects for a variety of symptoms. Its heady and stress-relieving effects can help manage symptoms associated with anxiety, depression, and other mental health disorders.

Eating and sleeping disorders can also be alleviated with its calming and sedating effects. Some patients have had success using this strain to treat nausea and minor aches and pains.

Its main selling point, the high THC content, can be debilitating for some. If you take higher doses than you're used to or if you're a new user, you can feel mild negative effects if you over-consume. Its high THC content can lead to paranoia and anxiety, especially if you're anxiety-prone. Otherwise, you may experience dry mouth and dry and itchy eyes, but overall a pleasant experience.

Feelings: Relaxed, Euphoric, Happy, Sleepy, Uplifted

Medical Uses: Stress, Anxiety, Pain, Insomnia, Depression

Negative Side Effects: Paranoia, Anxiety, Dry Mouth, Dry and Itchy Eyes

Products: Flower, Pre-Roll, Vape Cartridge, Wax, Live Resin

Appearance of Do-Si-Dos Strain

Do-Si-Dos' buds definitely elicit a double-take. This strain has an alluring lime green and lavender-colored hue. Bright and rusty-colored pistils offer a striking contrast of color.

Its glistening trichomes create a mesmerizing shine over its vibrant foliage. Its dense and resin-coated buds usually have an elongated shape showing off its OG genetics. It almost looks too good to break up and grind.

How to Grow Do-Si-Dos Weed Strain

One of the hardest parts about growing Do-Si-Dos is finding a quality seed. Currently, only regular Do-Si-Dos seeds are available. Feminized seeds are not. Plus, the rarity of this strain's seeds can make them quite expensive for first-time and budget growers.

If you're an experienced grower who wants to take on a new challenge, Do-Si-Dos is the strain to grow. If you're a beginner, you may want to start off with a similar and more widely available strain.

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Do-Si-Dos strain has a similar growth pattern to Girl Scout Cookies. This indica hybrid starts off as a short plant. Eventually, it shoots up and develops big internode gaps. During the flowering time, these spaces are filled out with average-sizes yields.

This strain's flowering period can take between 49 and 77 days, or 63 days on average. If you're growing this strain outdoors, make sure it's in a semi-humid climate with temperatures between 70º and 80º F.

Growing Difficulty: Intermediate

Plant Height: Medium

Flowering Period: 8-9 weeks

Yield: Moderate

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Gavin Kushman. Cannabis strain writer in a cannabis garden
Gavin Kushman

Gavin is a worldly adventurer and cannabis connoisseur, embarking on journeys that take him to the far corners of the globe to explore and document the varied effects, flavors, and histories of both renowned and lesser-known strains. From the misty high-altitude farms of the Hindu Kush highlands to the vibrant cannabis cafes of Amsterdam, Gavin's quest for knowledge spans continents. A recognized authority in the cannabis industry, he frequently lends his expertise to leading publications such as Cannabis Training University, where his captivating blog articles chronicle his unique experiences with different cannabis strains.

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